Synthesis of 1,5-Benzodiazepine Nucleosides

Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/19562

Title:	Synthesis of 1,5-Benzodiazepine Nucleosides
Authors:	'ROSHAN AHMAD M. ZIA-UL-HAQ SHAHID HAMEED HUMAIRA NADEEM DUDDECK, HELMUT
Issue Date:	4-Dec-2000
Publisher:	Karachi: International Centre for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi
Citation:	Yadav, A. K., Kumar, M., Yadav, T., & Jain, R. (2010). A novel one pot room temperature ionic liquid mediated synthesis of 1, 5-benzodiazepine ribofuranosides.
Abstract:	The phenolic beta -diketones I prepared by modified Baker-Venkataraman rearrangement were converted to benzodiazepine derivatives II by treatment with o-phenylenediamine. Coupling of benzodiazepine derivatives II with acetobromo sugars in presence of mercuric cyanide and nitromethane gave acetylated sugar derivatives of benzodiazepines III. The nucleosides IV were obtained by the deacetylation of compounds III. Structures of all intermediates and final products were confirmed with the help of modern spectroscopic methods.
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/19562
ISSN:	0253-5106
Appears in Collections:	Issue 04

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