SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF SOME ENAMINONES AND THEIR COMPLEXES WITH NICKEL (II) AND ANTIMONY (III)

Abstract

Enaminones; 4-N,N-diethylamine-pent-3-ene-2-one [HL1], 4-N,N-di-n-propylamine-pent-3-ene-2-one [HL2] and 4-N,N-dicyclohexylamine-pent-3-ene-2-one [HL3] and their complexes with Ni (II) and Sb (III) ions were prepared by reacting the equimolar ethanolic solutions of the ligands (HL1, HL2 and HL3) with ethanolic metal ion solutions. The synthesized metal complexes were characterized by infrared, UV/Visible and atomic absorption spectroscopy. Metal complexes of Ni (II) and Sb (III) ions thus prepared, showed coordination numbers, four and six respectively. They were tested for their antibacterial activity against Escherichia coli and Staphylococcus aureus, staphylococcus epidermidis bacteria. Ligands were completely inactive against bacteria whereas the complexes of Sb (III) with ligands (HL1, HL2 and HL3) have remarkable action on these bacteria, indicating that they have an ample potency as bactericide. Other complexes have normal bactericidal character.