Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the patients of Type II Diabetes Mellitus

Abstract

BACKGROUND: Diabetes mellitus and dyslipidemia with their complications disclose unscrupulous impact on human health, and increase the rate of mortality all over the world. The allopathic medicine is being used and consumed all over the world for the treatment of hazardous disease and their complications. Nowadays hypothesis has raised that natural production like olive oil and garlic etc having potential benefits to control glycemic control, blood cholesterol, triglycerides, lipoproteins (Low density lipoprotein & High density lipoprotein). AIMS & OBJECTIVE: To evaluate the effects of natural remedies (combination of olive oil & garlic) on serum cholesterol and serum triglyceride(TAG?s) levels with comparison to conventional allopathic (statin) therapy. METHODOLOGY: This Randomized Control Trial (RCT) study conducted at Institute of Biochemistry Sindh University Jamshoro with collaboration of diabetic clinic medical wards LUMHS Jamshoro. Total 160 patients recruited and divided into two groups as control and case study group. Anti diabetic and statin drugs were given to each group with same dose and balanced diet, formulated capsules containing 1.1 ml of olive oil & 500mgs of garlic powder were given only patients of case study group for 3 months. Biochemical analysis of serum cholesterol & serum TAG?s was done at zero level, level ? I & level ? II by enzymatic caloric method on Cobas auto analyzer. RESULTS: The study presented that serum cholesterol level & serum TAG?s levels were statistically normalized in case study group as compared to control group. CONCLUSION: The natural remedies (Phyto therapy) have an important role in the treatment of dyslipidemia in type ? II diabetic patients, so Phyto therapy can also takes part in the prevention of complications due to dyslipidemia in diabetic population.