Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/19764
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dc.contributor.authorMUHAMMAD IQBAL, CHOUDHARY-
dc.contributor.authorACHYUT ADHIKARI-
dc.contributor.authorSAMREEN-
dc.contributor.authorATTA-UR-RAHMAN-
dc.date.accessioned2023-10-03T05:26:15Z-
dc.date.available2023-10-03T05:26:15Z-
dc.date.issued2010-12-20-
dc.identifier.citationChoudhary, M. I., Adhikari, A., & Rahman, A. (2010). Antileishmanial steroidal alkaloids from roots of Sarcococca coriacea. J Chem Soc Pak, 32, 799-802.en_US
dc.identifier.issn0253-5106-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/19764-
dc.description.abstractBio-assay guided isolation of secondary metabolites from the plant Sarcococca coriacea (Hook. f.) yielded two steroidal alkaloids, alkaloid C (1) and iso-N-formylchonemorphine (2). The structures of compounds were identified by different spectroscopic techniques. Compounds 1 and 2 showed significant anti-leishmanial activities IC₅₀ = 13.20 ± 0.05 µM and 24.76 ± 0.01 µM, respectively, in comparison with standard drugs pentamidine IC₅₀ = 8.58 ± 0.04 µM and amphotericin B IC₅₀ = 0.31 ± 0.05 µM.en_US
dc.description.sponsorshipThe chemical society of Pakistan is an approved society from the PSF.en_US
dc.language.isoenen_US
dc.publisherHEJ Research Institute of Chemistry, University of Karachi, Karachi.en_US
dc.titleAntileishmanial Steroidal Alkaloids from Roots of Sarcococca coriaceaen_US
dc.typeArticleen_US
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