allo-Imperatorin: A Potent Urease Inhibitor from Fresh Unripe Fruits of Aegle marmelos (Rutaceae)

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Title:	allo-Imperatorin: A Potent Urease Inhibitor from Fresh Unripe Fruits of Aegle marmelos (Rutaceae)
Authors:	ALI, MUHAMMAD SHAIQ GHAFOOR AHMED PERVEZ, MUHAMMAD KASHIF MEHREEN LATEEF NIGHAT AFZA LUBNA IQBAL
Issue Date:	20-Dec-2011
Publisher:	HEJ Research Institute of Chemistry, University of Karachi, Karachi.
Citation:	Ali, M. S., Ahmed, G., Pervez, M. K., Lateef, M., Afza, N., & Iqbal, L. (2011). allo-Imperatorin: A potent urease inhibitor from fresh unripe fruits of Aegle marmelos (Rutaceae). Journal of the Chemical Society of Pakistan, 33(6), 960-964.
Abstract:	During the search for bioactive constituents from different parts of Aegle marmelos (Rutaceae), the ethanol soluble portion of fresh unripe fruits yielded two known amides named aegeline (1) and 2-O-methyl aegeline (2), and five known coumarins named xanthotoxol (3), alloimperatorin (4), marmesin (5), marmin (6), 7′-O-methylmarmin (7). Structures of 1-7 were elucidated with the aid of spectroscopic techniques. All the isolated constituents (1-7) were tested for urease inhibition. allo-Imperatorin was found the most potent among the all tested samples with the IC₅₀ value 27.5 µM.
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/19806
ISSN:	0253-5106
Appears in Collections:	Issue 06

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