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http://142.54.178.187:9060/xmlui/handle/123456789/19845| Title: | FACILE SYNTHESES OF BIOACTIVE 5-ARYLIDENETHIOBARBITURIC ACIDS |
| Authors: | Ahsan Sharif Ejaz Ahmad Munawar Ali Munawar Shamsa Jabeen Misbah-ul-Ain, Khan Robina Begum Aleeza Farrukh Muhammad Ashraf Shafia Arshad Nighat Afza |
| Issue Date: | 20-Aug-2011 |
| Publisher: | HEJ Research Institute of Chemistry, University of Karachi, Karachi. |
| Citation: | Sharif, A., Ahmed, E., Munawar, M. A., Jabeen, S., Khan, M. U. A., Begum, R., ... & Afza, N. (2011). Facile syntheses of bioactive 5-arylidenethiobarbituric acids. Journal of the chemical Society of Pakistan, 33(4), 578-586. |
| Abstract: | A simple and green chemistry route for the preparation of 5- arylidenethiobarbituric acids has been developed by Knoevenagel condensation of thiobarbituric acid with different aromatic and heteroaromatic aldehydes using catalytic amount of acetic acid by grinding in mortar and pestle. The title compounds were obtained in good to high yields (50-89%) and characterized by IR, NMR, mass spectroscopy and elemental analysis. All compounds exhibited DPPH radical scavenging and antibacterial activities, respectively. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/19845 |
| ISSN: | 0253-5106 |
| Appears in Collections: | Issue 04 |
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| issueDetail.aspx?aid=53b2a1e3-6db8-49e9-9e13-3724e8e72917.htm | 148 B | HTML | View/Open |
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