Synthesis, Crystal Structure and Biological activity of   N-(5-(o-tolyl)-1, 3, 4-thiadiazol-2-yl)cyclopropanecarboxamide

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Title:	Synthesis, Crystal Structure and Biological activity of N-(5-(o-tolyl)-1, 3, 4-thiadiazol-2-yl)cyclopropanecarboxamide
Authors:	Jian-Ying Na-Bo Sun Hong-Ke Wu Xing-Hai Liu
Keywords:	Crystal structure synthesis, 1,3,4-thiadiazole herbicidal activity fungicidal activity.
Issue Date:	20-Oct-2013
Publisher:	HEJ Research Institute of Chemistry, University of Karachi, Karachi.
Citation:	Tong, J. Y., Sun, N. B., & Wu, H. K. (2013). Synthesis, crystal structure and biological activity of N-(5-(O-tolyl)-1, 3, 4-thiadiazol-2-yl) cyclopropanecarboxamide. Journal of the Chemical Society of Pakistan, 35.
Abstract:	A new 1, 3, 4-thiadiazole compound, N-(5-(o-tolyl)-1,3,4-thiadiazol-2-yl) cyclopropanecarboxamide, was synthesized and its structure was confirmed by 1H NMR, MS and HRMS. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound has moderate herbicidal activity against Brassica campestris and fungicidal activities against Sclerotinia sclerotiorum(Lib.) de Bary, Rhizoctonia solanii, Fusarium oxysporum, Corynespora cassiicola, and Botrytis cinerea.
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/19866
ISSN:	0253-5106
Appears in Collections:	Issue 05

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