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  6. Journal of the Chemical Society of Pakistan
  7. Volume 32
  8. Issue 02
Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/19894
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dc.contributor.authorINAM-UL.-HAQUE-
dc.contributor.authorHINA SARA-
dc.date.accessioned2023-10-31T05:24:32Z-
dc.date.available2023-10-31T05:24:32Z-
dc.date.issued2010-04-19-
dc.identifier.citationKumar, A. S. H. U. T. O. S. H. (2016). Vincristine and vinblastine: a review. IJMPS, 6, 23-30.en_US
dc.identifier.issn0253-5106-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/19894-
dc.description.abstractVinblastine sulfate extracted from leaves of Catharanthus roseus is widely used as an anti-cancer drug. Chemically vinblastine is one of the Vinca alkaloids that inhibit the polymerization of tubulin, resulting in the disappearance of the microtubular spindle, and as a consequence they cause the arrest of cell division in their metaphase. There is limited information in the literature on the metabolism of vinblastine. 4-Deacetylvinblastine has been reported to be a urinary metabolite of vinblastine in dog and in humans. Determination and detection of vinblastine sulfate and its metabolites, by different methods, in biological samples is reviewed from 1972 to 2009.en_US
dc.description.sponsorshipThe chemical society of Pakistan is an approved society from the PSF.en_US
dc.language.isoenen_US
dc.publisherHEJ Research Institute of Chemistry, University of Karachi, Karachi.en_US
dc.titleVinblastine: A Reviewen_US
dc.typeArticleen_US
Appears in Collections:Issue 02

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