Optimization of the Extraction of Flavonoids from Grape Leaves by Response Surface Methodology

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Title:	Optimization of the Extraction of Flavonoids from Grape Leaves by Response Surface Methodology
Authors:	KORBANJHON BRAD YAN ZHANG WEI LIU
Keywords:	Optimization Response surface methodology Flavonoids Extraction Grape leaves
Issue Date:	7-Aug-2013
Publisher:	HEJ Research Institute of Chemistry, University of Karachi, Karachi.
Citation:	Brad, K., Liu, W., & Zhang, Y. (2013). Optimization of the extraction of flavonoids from grape leaves by response surface methodology. Journal of the Chemical Society of Pakistan, 35(4), 1103-1105.
Abstract:	The extraction of flavonoids from grape leaves was optimized to maximize flavonoids yield in this study. A central composite design of response surface methodology involving extracting time, power, liquid-solid ratio, and concentration was used, and second-order model for Y was employed to generate the response surfaces. The optimum condition for flavonoids yield was determined as follows: extracting time 24.95 min, power 72.05, ethanol concentration 63.35%, liquid-solid ratio 10.04. Under the optimum condition, the flavonoids yield was 76.84 %.
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/19952
ISSN:	0253-5106
Appears in Collections:	Issue 04

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