Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/19998
Title: Spectrophotometric Determination of Diazepam
Authors: WASEEM ASGHAR KHAN
NARJIS NAZ
NAVEED ASLAM DOGER
NAEEM ASGHAR KHAN
NADEEM ASGHAR KHAN
Keywords: Diazepam
Ninhydrin
Spectrophotometric Determination
Issue Date: 20-Jun-2012
Publisher: HEJ Research Institute of Chemistry, University of Karachi, Karachi.
Citation: KHAN, N. A., Naz, N., KHAN, N. A., DOGER, N. A., & KHAN, W. A. (2012). Spectrophotometric Determination of Diazepam. Journal of the Chemical Society of Pakistan, 34(6), 536.
Abstract: Diazepam reacts with ninhydrin at pH range 12-12.5 to give a violet color having maximum absorbance at 530 nm wavelength. The reaction is specific for diazepam and provides a basis for its spectrophotometric determination. The color reaction obeys Beer’s law from 0.1 to 2 mg/10 mL of diazepam. Coefficient of variation and confidence limit determination are 0.06 and 0.0041%, respectively. The relative standard deviation is 1.5%. The quantitative assessments of tolerable amount of other drugs have also been studied
URI: http://142.54.178.187:9060/xmlui/handle/123456789/19998
ISSN: 0253-5106
Appears in Collections:Issue 03

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