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  1. Pastic Digital Repository
  2. MoST Organizations
  3. Pakistan Science Foundation
  4. Pakistan Science Foundation
  5. PSF Research Support (Scientific Research Journals)
  6. Journal of the Chemical Society of Pakistan
  7. Volume 34
  8. Issue 03
Please use this identifier to cite or link to this item: http://142.54.178.187:9060/xmlui/handle/123456789/20015
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dc.contributor.authorIRSHAD AHMAD-
dc.contributor.authorBASHIR AHMAD CHAUDHARY-
dc.contributor.authorMUHAMMAD ASHRAF-
dc.contributor.authorMUHAMMAD UZAIR-
dc.contributor.authorKHALID HUSSAIN JANBAZ-
dc.date.accessioned2023-12-08T06:03:12Z-
dc.date.available2023-12-08T06:03:12Z-
dc.date.issued2012-06-20-
dc.identifier.citationAhmad, I., Chaudhary, B. A., Ashraf, M., Uzair, M., & Janbaz, K. H. (2012). Vernonione, a new urease inhibitory carvotacetone derivative from Vernonia cinerascens. Journal of the Chemical Society of Pakistan, 34(3).en_US
dc.identifier.issn0253-5106-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/20015-
dc.description.abstractVernonione, a new 7-deoxycarvotacetone derivative 1, together with three known sesquiterpene lactones; vernolide A, C (2,3) and potamopholide (4) has been isolated from the methanolic extract of the roots of Vernonia cinerascens. The structure 3β-acetoxy-5α-angeloyloxy7-deoxycarvotacetone was established by using UV, IR, ¹H and ¹³C-NMR spectra (DEPT), 2D-NMR analyses (COSY, HMQC and HMBC experiments) in combination with HRFAB-MS, HREI-MS experiments and in comparison with literature data of related compounds. Compound 1 showed inhibitory potential against enzyme urease in concentration dependant fashion with IC₅₀ value 227.6 µmol.en_US
dc.description.sponsorshipThe chemical society of Pakistan is an approved society from the PSF.en_US
dc.language.isoenen_US
dc.publisherHEJ Research Institute of Chemistry, University of Karachi, Karachi.en_US
dc.titleVernonione, A New Urease Inhibitory Carvotacetone Derivative from Vernonia cinerascensen_US
dc.typeArticleen_US
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