Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/982
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dc.contributor.authorBeenish Israr*-
dc.contributor.authorRichard Andrew Frazier-
dc.contributor.authorMicheal Hodson Gordon-
dc.date.accessioned2019-11-07T10:12:38Z-
dc.date.available2019-11-07T10:12:38Z-
dc.date.issued2019-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/982-
dc.description.abstractBioavailabilityofoxalateishighlyinfluencedbythepresenceofmetalcationsinthegastrointestinaltractasaresultofthedifferentsolubilityofoxalatesalts.BioavailabilityisfurtherinfluencedbypHeffectsonoxalatesolubilityatvariousstagesofdigestion,particularlyatgastricpHatwhichinsolubleoxalatehasbeenfoundtosolubilize.TheaimofthepresentstudywastoassesstheeffectofgastrointestinalpHanddifferentmetalionsontherelativesolubilityofoxalateaftertreatmentwithrelevantgastricandintestinalenzymesinsimulatedgastrointestinaldigestionconditions.Wholebrancerealsandbeanswereusedastestsamples.Oxalatesolubilityincreasedalongwithreproduciblerecoverysuchas97±4atgastricpH-2comparedtohigherpH.Highamountofsolubleoxalate(32±1.2)wasfoundinwheatbranaftersimulatedinvitrodigestionundergastricconditionsascomparedtointestinalconditionsi.e.11±0.5.Theavailabilityofcalciumforabsorptionwasfoundtobeverylowcomparedtothatofmagnesiumandpotassiumi.e.,15±0.3,13±0.5to10±0.42and4±1inwheatbransampleatgastricandintestinalconditionssimultaneously.Theformationofacomplexbetweencalciumandoxalatereducedsolubilityandhencemadecalciumlessavailableforabsorption.Presenceofmetalsandoxalatenotonlyreducesoxalateavailability,butitalsoreducesavailabilityofmetalcationsen_US
dc.language.isoen_USen_US
dc.publisherPakistan Journal of Agricultural Sciences, Faisalabad,en_US
dc.subjectOrganic aciden_US
dc.subjectcalcium regulationen_US
dc.subjectgastric pHen_US
dc.subjectsoluble oxalateen_US
dc.subjectsoluble saltsen_US
dc.subjectmetal detoxificationen_US
dc.subjectAgriculture Scienceen_US
dc.titleSOLUBILITY OF OXALATE AND ITS ASSOCIATION WITH METAL IONS ASSESSED BY A SIMULATED IN VITRODIGESTION MODELen_US
dc.typeArticleen_US
Appears in Collections:Agriculture Thesis

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