Please use this identifier to cite or link to this item:
http://localhost:80/xmlui/handle/123456789/13777
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Begum, Nasreen | - |
dc.contributor.author | Anis, Itrat | - |
dc.contributor.author | Saeed, Syed Muhammad Ghufran | - |
dc.contributor.author | Ashraf, Seema | - |
dc.contributor.author | Choudhary, M. Iqbal | - |
dc.date.accessioned | 2022-10-27T10:30:19Z | - |
dc.date.available | 2022-10-27T10:30:19Z | - |
dc.date.issued | 2020-03-16 | - |
dc.identifier.issn | 1011-601X | - |
dc.identifier.uri | http://142.54.178.187:9060/xmlui/handle/123456789/13777 | - |
dc.description.abstract | We report here the synthesis as well as antioxidant activity of a series of 2-aryl thiazolidine-4-carboxylic acids, including two novel derivatives. They were synthesized by nucleophilic cyclic condensation of L-cysteine hydrochloride with a range of aromatic aldehydes. Their in vitro antioxidant activity was evaluated by DPPH radical scavenging assay. It was observed that the aromatic substituent at C-2 of thiazolidine ring effects the antioxidant potential of the thiazolidine derivatives. The nature and position of the substituents on aromatic ring were correlated with antioxidant activity. Compounds with -OCH3 group on aromatic ring showed a better radical scavenging property than the other groups such as -Cl, -F, and -NO2. The presence of phenyl ring thus enhanced radical scavenging activity. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Karachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachi | en_US |
dc.subject | Antioxidant activity | en_US |
dc.subject | DPPH | en_US |
dc.subject | L-cysteine | en_US |
dc.subject | free radical scavenging | en_US |
dc.subject | (4R) Thiazolidine carboxylic acid | en_US |
dc.title | Synthesis of (4R)-thiazolidine carboxylic acid and evaluation of antioxidant potential | en_US |
dc.type | Article | en_US |
Appears in Collections: | Issue 2 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Paper-10.htm | 131 B | HTML | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.