Please use this identifier to cite or link to this item: http://localhost:80/xmlui/handle/123456789/13777
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dc.contributor.authorBegum, Nasreen-
dc.contributor.authorAnis, Itrat-
dc.contributor.authorSaeed, Syed Muhammad Ghufran-
dc.contributor.authorAshraf, Seema-
dc.contributor.authorChoudhary, M. Iqbal-
dc.date.accessioned2022-10-27T10:30:19Z-
dc.date.available2022-10-27T10:30:19Z-
dc.date.issued2020-03-16-
dc.identifier.issn1011-601X-
dc.identifier.urihttp://142.54.178.187:9060/xmlui/handle/123456789/13777-
dc.description.abstractWe report here the synthesis as well as antioxidant activity of a series of 2-aryl thiazolidine-4-carboxylic acids, including two novel derivatives. They were synthesized by nucleophilic cyclic condensation of L-cysteine hydrochloride with a range of aromatic aldehydes. Their in vitro antioxidant activity was evaluated by DPPH radical scavenging assay. It was observed that the aromatic substituent at C-2 of thiazolidine ring effects the antioxidant potential of the thiazolidine derivatives. The nature and position of the substituents on aromatic ring were correlated with antioxidant activity. Compounds with -OCH3 group on aromatic ring showed a better radical scavenging property than the other groups such as -Cl, -F, and -NO2. The presence of phenyl ring thus enhanced radical scavenging activity.en_US
dc.language.isoenen_US
dc.publisherKarachi: Faculty of Pharmacy & Pharmaceutical Sciecnes, University of Karachien_US
dc.subjectAntioxidant activityen_US
dc.subjectDPPHen_US
dc.subjectL-cysteineen_US
dc.subjectfree radical scavengingen_US
dc.subject(4R) Thiazolidine carboxylic aciden_US
dc.titleSynthesis of (4R)-thiazolidine carboxylic acid and evaluation of antioxidant potentialen_US
dc.typeArticleen_US
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