Anti-hyperglycemic potential of Lactobacillus spp. in alloxan-induced Wistar rats

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Title:	Anti-hyperglycemic potential of Lactobacillus spp. in alloxan-induced Wistar rats
Authors:	Bharti, Vandana Mehta, Archana Mourya, Gajendra Kumar Ahirwal, Laxmi Bajpai, Vivek K Shukla, Shruti
Keywords:	Lactobacillus spp diabetes dairy products body weigh
Issue Date:	Mar-2017
Publisher:	Faculty of Pharmacy & Pharmaceutical Sciences
Citation:	Bharti, V., Mehta, A., Mourya, G. K., Ahirwal, L., Bajpai, V. K., & Shukla, S. (2017). Anti-hyperglycemic potential of Lactobacillus spp. in alloxan-induced wistar rats. Pak J Pharm Sci, 30, 597-600.
Abstract:	This research was aimed to investigate anti-hyperglycemic effects of two Lactobacillus spp. on alloxan induced diabetic rats. Alloxan was administered intraperitoneally to induce the diabetic conditions in experimental rats. Animals were treated with oral administration of Lactobacillus spp., such as L. plantarum and L. acidophilus at the dose of 10 8 CFU/ml. As a result, administration of Lactobacillus spp. significantly (P<0.05) lowered blood glucose levels in diabetic rats by (201-220mg/dl) as compared to diabetic control (265mg/dl). Also, both the Lactobacillus spp. were able to reduce body weight of experimental animals as compared to control group, suggesting potent anti-hyperglycemic effect of Lactobacillus spp. in terms of their anti-diabetic potential
URI:	http://142.54.178.187:9060/xmlui/handle/123456789/13921
ISSN:	1011-601X
Appears in Collections:	No.2(Supplementary),March 2017

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