Please use this identifier to cite or link to this item:
http://142.54.178.187:9060/xmlui/handle/123456789/19894| Title: | Vinblastine: A Review |
| Authors: | INAM-UL.-HAQUE HINA SARA |
| Issue Date: | 19-Apr-2010 |
| Publisher: | HEJ Research Institute of Chemistry, University of Karachi, Karachi. |
| Citation: | Kumar, A. S. H. U. T. O. S. H. (2016). Vincristine and vinblastine: a review. IJMPS, 6, 23-30. |
| Abstract: | Vinblastine sulfate extracted from leaves of Catharanthus roseus is widely used as an anti-cancer drug. Chemically vinblastine is one of the Vinca alkaloids that inhibit the polymerization of tubulin, resulting in the disappearance of the microtubular spindle, and as a consequence they cause the arrest of cell division in their metaphase. There is limited information in the literature on the metabolism of vinblastine. 4-Deacetylvinblastine has been reported to be a urinary metabolite of vinblastine in dog and in humans. Determination and detection of vinblastine sulfate and its metabolites, by different methods, in biological samples is reviewed from 1972 to 2009. |
| URI: | http://142.54.178.187:9060/xmlui/handle/123456789/19894 |
| ISSN: | 0253-5106 |
| Appears in Collections: | Issue 02 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 808-3401-1-RV.htm | 122 B | HTML | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.